REHABILITATION OF PATIENTS WITH CHRONIC LIVER DISEASES AND ITS EFFICIENCY MONITORING IN THE INCREASED RADIATION RISK REGION OF EAST KAZAKHSTAN AREA

Post date: 04-12-2014 Author(s): Z.K. Zhumadilova1, N.R. Barkibaeva1, L.T. Kassym1, A.Yu. Kravchenko2, A.Sh. Kaskabaeva1, Zh.E. Muzdubaeva1, A.O. Kulmagambetov3 1 Semey State Medical University, Republic of Kazakhstan, 2 Barnaul Emergency Rescue Hospital, Russian Federation, 3 Medical Center of Semey State Medical University, Republic of Kazakhstan

Summary The possibilities of noninvasive evaluation of the fibrosis formation were recognized by using discriminant score scale in comparison with the indicators of hepatic hemodynamics. The antiproliferating properties of carnitine complex treatmentamong the East Kazakhstan residents exposed to radiation with chronic liver disease were identified.   Key words: Ionizing radiation, liver cirr... more

год: 2014 выпуск №2

MICROSCOPIC PECULIARITIES OF DIFFERENT FORM OF GASTROESOPHAGEAL REFLUX DISEASE

Post date: 04-12-2014 Author(s): V.V. Gargin, V.V. Sakal Kharkiv National Medical University, Ukraine Institute of Therapy named after L.T. Malaya NAMS of Ukraine

Summary Thework devoted for investigation of the prevalence and significance of microscopic changes in the esophageal mucosa in gastroesophageal reflux disease (GERD) for the biopsy results. It was studied 223 patients with biopsy, which have been diagnosed with GERD. Material was divided after comparing endoscopic and histological data into three subgroups: non-erosive GERD was referred 104 ca... more

год: 2014 выпуск №2

DENTAL STATUS OF PATIENTS DURING THE SUPPORTIVE CARE AT ANTINEOPLASTIC CHEMOTHERAPY FOR BREAST CANCER

Post date: 04-12-2014 Author(s): I.S. Sukhina Kharkоv National Medical University, Kharkоv, Ukraine

Abstract Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemotherapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has ... more

год: 2014 выпуск №4

CANCER MORBIDITY IN PATIENTS WITH DIABETES MELLITUS

Post date: 04-12-2014 Author(s): S. Iskakova1 , O. Urazayev1, E. Bekmukhambetov1, G. Dworacki2 1West-Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan; 2 Poznan University of Medical Science, Poznan, Poland

Despite the progress in health care, the incidence of malignant neoplasms (MN) continues to increase. According to WHO (2013) annually in all over the world primary cancers are detected in 9 million people and cause death of about 5 million people a year. Every day in Kazakhstan more than 80 people develop cancer, and the increase in the number of patients with malignant neoplasms is 5% a year. T... more

год: 2014 выпуск №4

ASSOCIATION BETWEEN 53BP1 EXPRESSION AND GENOMIC INSTABILITY IN ONCOCYTIC FOLLICULAR ADENOMA OF THE THYROID

Post date: 04-12-2014 Author(s): Zhanna Mussazhanova1, Kazuko Shichijo2, Shiro Miura2, Katsuya Matsuda2, Ryota Otsubo2, Masahiro Oikawa3, Kohichiro Yoshiura4, Norisato Mitsutake4, Tatiana Rougounovitch4, Vladimir Saenko4, Hisayoshi Kondo5, Masahiro Ito3, Masahiro Nakashima2* 1Research center, Semey State Medical University, Semey, Kazakhstan; 2Department of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan 3Department of Pathology, National Hospital Organization Nagasaki Medical Center, Omura, Japan 4Department of Radiation Medical Sciences, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan 5Biostatics Section, Division of Scientific Data Registry, Atomic Bomb Disease Institute, Nagasaki Uni-versity Graduate School of Biomedical Sciences, Nagasaki, Japan

We have reported a usefulness of immunofluorescence (IF) analysis for the type of 53BP1 expression, which belongs to DNA damage response (DDR) molecules, to estimate the genomic instability (GIN) in diverse tumorigenesis including thyroid. The expression of 53BP1 nuclear foci (NF) has been found to reflect DNA double strand break caused by various stresses. Accumulation of genetic mutations can i... more

год: 2014 выпуск №4